Changes of End of Life Practices for Cancer Patients and TheirAssociation with Hospice Palliative Care Referral over 2009-2014:A Single Institution Study / Journal of the Korean Cancer Association, 대한암학회지

Purpose@#In Korea, hospice palliative care (HPC) provision for cancer patients has increased recently.However, whether end of life (EoL) care practices have improved along with the developmentof HPC is unclear. We intended to investigate the changes in EoL care practices and theirassociation with HPC referral. @*Materials and Methods@#Retrospective medical record review of adult cancer patients who died at National CancerCenter Korea from 1 January 2009 to 31 December 2014 was performed. Changes of EoLpractices including chemotherapy within 2 weeks from death, death in intensive care unit(ICU), documentation of “do not resuscitate (DNR)” within 7 days from death and referral toHPC from 2009 to 2014 were analyzed as well as the association between referral to HPCand other practices. @*Results@#A total of 2,377 cases were included in the analysis. Between 2009 and 2014, referral toHPC increased and DNR documentation within 7 days from death decreased significantly.Cases for chemotherapy within 2 weeks from death and death in ICU didn’t change overthe study period. Patients referred to HPC were less likely to receive chemotherapy within2 weeks from death, die in ICU and document DNR within 7 days from death. @*Conclusion@#During the study period, EoL practices among cancer patients partly changed toward lessaggressive in our institution. HPC referral was associated with less aggressive cancer careat the EoL. Policies to promote EoL discussion are necessary to improve the EoL practicesof cancer patients.

Severe Hypocalcemia in a Patient with Recurrent Chondrosarcoma.

Hypocalcemia is relatively uncommon paraneoplastic syndrome. Only one case of hypocalcemia has been reported in a patient with chondrosarcoma. We herein report a case of a 32-year-old woman with metastatic chondrosarcoma with tetany. Her imaging findings revealed multiple calcific metastatic lesions in the lungs, pancreas, left atrium, and pulmonary vein. A laboratory examination showed hypocalcemia with no evidence of any other disease that could induce hypocalcemia. On the basis of the laboratory and clinical findings, we concluded the etiology of her severe hypocalcemia to be excessive calcium consumption by the tumor itself.

A Case of Chylopericardium Secondary to the Superior Vena Cava Syndrome in Behcet's Disease / 대한류마티스학회지

Behcet's disease (BD) is a chronic inflammatory disorder associated with oral aphthous ulcer, genital ulcer and uveitis. Vascular lesions in BD can affect all types and sizes of vessels. The venous thrombosis, which is uncommon feature of other vasculitis, is relatively common clinical manifestation of BD. Sometimes the cardiovascular involvement in BD results in serious complications as the leading cause of morbidity and mortality. We report a 41-year-old male patient who suffered BD and presented massive chylopericardium due to the superior vena cava (SVC) syndrome. After thrombectomy of SVC, the highly productive left-sided chylothorax and restenosis of anastomosis site at SVC had occurred, which were successfully treated by the ligation of the thoracic duct and balloon-stent angioplasty. We discussed the mechanism and treatment of chylopericardium in SVC syndrome, and the possible complications after the surgical management.